Optimum Conditions for the 13C-Phenylalanine Breath Test.
نویسندگان
چکیده
منابع مشابه
Gender affects 13C-ketoisocaproic acid breath test.
BACKGROUND AND AIMS 13C-Ketoisocaproic Acid Breath Test (13C-Kica-BT) has been proposed to assess mitochondrial function. Aim of this study is to evaluate whether gender affects mithocondrial oxidation by means of 13C-Kica-BT in healthy subjects in basal conditions and after an acute oxidative stress induced by ethanol. METHODOLOGY 50 healthy volunteers were given 1 mg/kg of 13C-Kica together...
متن کاملLow dose capsule based 13c-urea breath test compared with the conventional 13c-urea breath test and invasive tests.
CONTEXT One of the limitations of 13C-urea breath test for Helicobacter pylori infection diagnosis in Brazil is the substrate acquisition in capsule presentation. OBJECTIVES The purpose of this study was to evaluate a capsule-based 13C-urea, manipulated by the Pharmacy Division, for the clinical practice. METHODS Fifty patients underwent the conventional and the capsule breath test. Samples...
متن کاملA Preliminary Study of 13C-Phenylalanine and 13C-Dipeptide Breath Tests in Horses
This study aimed to establish a standard dose and sample collection time for (13)C phenylalanine and (13)C-Dipeptide breath test in horses. To evaluate dose-dependent effects, healthy horses received 2.5 mg/kg, 5 mg/kg, and 10 mg/kg (13)C phenylalanine dissolved in 1 ml/kg distilled water and 1.25 mg/kg, 2.5 mg/kg, and 5 mg/kg (13)C dipeptide dissolved in 2 ml/ kg distilled water. Tmax was obse...
متن کاملPhenylalanine kinetics in healthy volunteers and liver cirrhotics: implications for the phenylalanine breath test.
Expired 13CO2 recovery from an oral l-[1-13C]phenylalanine ([13C]Phe) dose has been used to quantify liver function. This parameter, however, does not depend solely on liver function but also on total CO2 production, Phe turnover, and initial tracer distribution. Therefore, we evaluated the impact of these factors on breath test values. Nine ethyl-toxic cirrhotic patients and nine control subje...
متن کاملClinical research on liver reserve function by 13C-phenylalanine breath test in aged patients with chronic liver diseases
BACKGROUND The objective of this study was to investigate whether the 13C-phenylalanine breath test could be useful for the evaluation of hepatic function in elderly volunteers and patients with chronic hepatitis B and liver cirrhosis. METHODS L-[1-13C] phenylalanine was administered orally at a dose of 100 mg to 55 elderly patients with liver cirrhosis, 30 patients with chronic hepatitis B a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1998
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.46.1330